October 16, 2007
Resveratrol May Also be Powerful Against Diabetes
Resveratrol is a substance found in red wine and the skin of red grapes. You have probably heard of some of the prior research which has indicated that it has anti-aging, anti-inflammatory, anti-cancer and life extension benefits. Now to that list we can add the possibillity that resveratrol is beginning to look like a promising weapon against type 2 diabetes.
Type 2 diabetes was formerly referred to as “adult-onset” diabetes. It causes cells to become less sensitive to the effects of insulin, as opposed to type 1 diabetes (formerly called juvenile diabetes), where the body just does not produce enough insulin.
Researchers at the Chinese Academy of Sciences found that in animal studies, resveratrol improves insulin sensitivity by activating an enzyme which in turn supresses a molecule that tends to decrease insulin activity.
Of course, further testing is required to confirm that the findings will translate to different animals and humans. One encouraging finding was that much lower doses of resveratrol were required than in previous studies.
In addition to grapes, grape juice and wine, resveratrol is found in varying amounts in a number of types of berries, plums and peanuts, and nutritional supplements are widely available. An interesting sidenote is that resveratrol in many ways seems to duplicate the biochemical effects of caloric restriction, so far the only reliable way that researchers have found to extend lifespan.
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